Human recombinant laminin-121
THIS PRODUCTS IS CURRENTLY ONLY AVAILABLE AS PROTOTYPE MATERIAL
Recreating the natural cell niche is key to successful cultivation. The physical, topological, and biochemical expression of the different laminin isoforms in the BM is heterogeneous and tissue specific.
Laminins-111/121 are widely expressed during embryogenesis, important for early epithelial development and differentiation of the epiblast thus vital for the development of an embryo However, the tissue distribution after birth is restricted to only a few tissues, such as brain and kidney.
Laminin-121 can be used as a general attachment protein for most cell types in vitro and in particular for hepatic and neural differentiation, and to enhance neurite outgrowth.
Not sure how much laminin you need? To make it easy, we have created a tool where you can calculate the amount needed for your experiments. Just choose culture well format and fill in the desired coating concentration to see the amount required.