A switch in Lamb2 to Lamb1 isoforms during aging controls endothelial cell functions and enhances endothelial-to-mesenchymal transition
Here, PhD student Julian Wagner decipher the role of the microenvironment underlying the impairment of endothelial cell functions by aging. Mimicking age-related modulation of laminin β1 versus β2 chain expression changes the functional properties and phenotype of endothelial cells.
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Julian U.G. Wagner, Goethe University, Germany