Human recombinant laminin-111
Recreating the natural cell niche is key to successful cultivation. The physical, topological, and biochemical expression of the different laminin isoforms in the BM is heterogeneous and tissue specific.
Human recombinant laminin-111 is important during early epithelial development and differentiation of the epiblast. Laminin-111 is up-regulated and widely expressed during embryogenesis, vital for the development of an embryo. However, its tissue distribution after birth is restricted to only a few tissues, such as brain and kidney. Laminin-111 is commonly used as a general attachment protein for most cell types in vitro and LN111 have been used successfully for hepatic and neural differentiation.
Not sure how much laminin you need? To make it easy, we have created a tool where you can calculate the amount needed for your experiments. Just choose culture well format and fill in the desired coating concentration to see the amount required.