Human recombinant laminin-511
Human recombinant laminin-511 (LN-511) is the natural laminin for mouse embryonic stem cells with sustained pluripotency without the need to use feeder cells or differentiation inhibitors like LIF.
Laminin-511 is together with laminin-521 (LN-521) the most widely expressed laminins in the body. LN-511 is especially recommended for cell culture of murine embryonic stem cells or induced pluripotent stem cells while LN-521 is recommended for human pluripotent stem cells.
Culture of mouse pluripotent stem cells on LN-511, which is already expressed at the 4‑cell stage during embryonic development, maintains the pluripotency without the use of LIF. Using LN-511 for adherent murine stem cell cultures makes culturing easy and efficient.
Not sure how much laminin you need? To make it easy, we have created a tool where you can calculate the amount needed for your experiments. Just choose culture well format and fill in the desired coating concentration to see the amount required.