Biolaminin 511 LN
Biolaminin 511 LN (LN511)
Human recombinant laminin 511
Human recombinant laminin 511, Biolaminin 511 LN (LN511), is the natural laminin for mouse embryonic stem cells with sustained pluripotency without the need to use feeder cells or differentiation inhibitors like LIF.
Laminin 511 is together with laminin 521 the most widely expressed laminins in the body. LN511 is especially recommended for cell culture of murine embryonic stem cells or induced pluripotent stem cells while LN521 is recommended for human pluripotent stem cells.
Culture of mouse pluripotent stem cells on LN511, which is already expressed at the 4‑cell stage during embryonic development, maintains the pluripotency without the use of LIF. Using LN511 for adherent murine stem cell cultures makes culturing easy and efficient.
Not sure how much laminin you need? To make it easy, we have created a tool where you can calculate the amount needed for your experiments. Just choose culture well format and fill in the desired coating concentration to see the amount required.