Human recombinant laminin-521
Recreating the natural cell niche is key to successful cultivation. The physical, topological, and biochemical expression of the different laminin isoforms in the BM is heterogeneous and tissue specific.
Laminin-521 (LN-521) is the natural laminin for pluripotent stem cells and therefore reliably facilitates self-renewal of human ES and iPS cells in a chemically defined, feeder-free and xeno-free stem cell culture system. LN-521 enables efficient single-cell passaging of genetically stable and pluripotent stem cells without need of any apoptosis inhibitors for superior quality of your cells and studies.
After birth, α5-laminins represent the most common laminins in the body and LN-521 supports many diverse tissue cell types, such as cells from pancreas, vascular, nervous and muscular systems.
Not sure how much laminin you need? To make it easy, we have created a tool where you can calculate the amount needed for your experiments. Just choose culture well format and fill in the desired coating concentration to see the amount required.